S.D. McAllister, G. Rizvi, S. Anavi-Goffer, D.P. Hurst, J. Barnett-Norris, D.L. Lynch, P.H. Reggio and M.E. Abood. "An Aromatic Microdomain at the Cannabinoid CB1 Receptor Constitutes an Agonist/Inverse Agonist Binding Region." J. Med. Chem. 46, 5139-5152 (2003). *PDF* (12)

P.H.Reggio. "Pharmacophores for Ligand Recognition and Activation/Inactivation of the Cannabinoid Receptors." Current Pharmaceutical Design. 9, 1607-1633 (2003). *PDF* (11)
J.W. Huffman, R. Mabon, M-J Wua, J. Lu, R. Hart, D.P. Hurst, P.H. Reggio, J.L. Wiley and B.R. Martin. "3-Indolyl-1-naphthylmethanes: New Cannabimimetic Indoles Provide Evidence for Aromatic Stacking Interactions with the CB1 Cannabinoid Receptor." Bioorg. Med. Chem. 11, 539-549 (2003). *PDF* (10)
R. Singh, D.P. Hurst, J. Barnett-Norris, D.L. Lynch, F. Guarnieri, P.H. Reggio. "Activation of the Cannabinoid CB1 Receptor May Involve a W6.48/F3.36 Rotamer Toggle Switch." J. Pep. Res. 60, 357-370 (2002). *PDF* (9)

J. Barnett-Norris, D.P. Hurst, D.L. Lynch, F. Guarnieri, A. Makriyanis and P.H. Reggio, "Conformational Memories and the Endocannabinoid Binding Site at the Cannabinoid CB1 Receptor." J. Med. Chem. 45, 3649-3659 (2002). *PDF* (8)

D.P. Hurst, D.L. Lynch, J. Barnett-Norris, S.M. Hyatt, H.H. Seltzman, M. Zhong, Z-H Song, J. Nie, D. Lewis and P.H. Reggio. "N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide Interaction with Lys 3.28(192) is Crucial for Its Inverse Agonism at the Cannabinoid CB1 Receptor." Mol. Pharmacol. 62, 1274-1287 (2002).   *PDF* (7)

P.H. Reggio, "Endocannabinoid Structure Activity Relationships for Interaction at the Cannabinoid Receptors," Prost. Leuk. Ess. Fatty Acids 66, 143-160 (2002). *PDF* (6)

P.H. Reggio and H. Traore, "Structure-Activity Relationships for Endocannabinoid Interaction with the Cannabinoid Receptor, the Anandamide Transporter and the Anandamide Amidohydrolase", Chem. Phys. Lipids 108,15-35 (2000). *PDF* (5)

Z.H. Song, C-A Slowey, D.P. Hurst and P.H. Reggio, "The Difference Between the CB1 and CB2 Cannabinoid Receptors at Position 5.46 is Crucial for the Selectivity of WIN55,212-2 for CB2." Mol. Pharmacol. 56, 834-840 (1999).   *PDF* (4)

Q. Tao, S.D. McAllister, J. Andreassi, K.W. Nowell, G.A. Cabral, D.P. Hurst, P.H. Reggio and M.E. Abood, "Role of a Conserved Lysine Residue in the CB2 Cannabinoid Receptor: Evidence for Sub-Type Specificity" Mol. Pharmacol. 55, 605-613 (1999).   *PDF* (3)

J. Barnett-Norris, F. Guarnieri, D.P. Hurst and P.H. Reggio, "Exploration of Biologically Relevant Conformations of Anandamide, 2-Arachidonylglycerol, and Their Analogs Using Conformational Memories" J. Med. Chem. 41, 4861- 4872 (1998). *PDF* (2)

P.H. Reggio, S. Basu-Dutt, J. Barnett-Norris, M.T. Castro, D.P. Hurst, H.H. Seltzman, M.J. Roche, A.F. Gilliam, B.F. Thomas, L.A. Stevenson, R.G. Pertwee and M.E. Abood, "The Bioactive Conformation of Aminoalkylindoles at the Cannabinoid CB1 and CB2 Receptors: Insights Gained from E and Z Naphthylindenes" J. Med Chem. 41, 5177-5187 (1998). *PDF* (1)

Return to Dr. Reggio's Home Page